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A bile supplement could be beneficial here Dec 30, · Xifaxan comes as a tablet to take by mouth with or without food. Patients who experience a recurrence of symptoms can be retreated up to two times with the same dosage regimen. What happens when you stop taking Xifaxan? When Xifaxan is used to treat traveler’s diarrhea, it is usually taken three times a day for 3 days. For IBS, it is usually taken for 2 weeks at a time. 10 For SIBO patients, the typical dosage of rifaximin is 550 mg 3 times per day for 2 weeks, which is way less than what’s been safely studied You may take this medicine with or without food. Follow your doctor’s dosing instructions very carefully. Hi everyone just have one question What is Xifaxan what does it do My mum is taking lactulose 20ml three times a day and is still confused You may take this medicine with or without food. 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